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. 2014 Apr 10;9(4):e86111. doi: 10.1371/journal.pone.0086111

Figure 2. Analysis of the expression of mucins by immunohistochemistry.

Figure 2

In mucins with increased expression in SBC, MUC1 showed apical and cytoplasmic expression in cancer cells, but not in the normal epithelium (A and B); MUC5AC showed cytoplasmic expression in cancer cells, but not in the normal epithelium (C and D); and MUC16 showed apical expression in cancer cells, but not in the normal epithelium (E and F). In mucins with equal expression in SBC, MUC4 showed cytoplasmic expression in normal epithelium and cancer cells (G and H); and MUC6 showed cytoplasmic expression in normal epithelium (insets) and cancer cells (I and J). In mucins with decreased expression in SBCs, MUC2 showed cytoplasmic expression in normal epithelium, but not in cancer cells (K and L); and MUC3 showed apical expression in normal epithelium, but not in cancer cells (M and N).