Table 1. Survival analysis using Cox proportional hazard models* with incorporation of curability.
D/T | P-y | HR | 95% CI | ||
Histological type | well, mod | 19/49 | 166.7 | 1.0 | reference |
poor, NEC | 5/6 | 4.1 | 8.0 | 2.5–26 | |
muc | 0/3 | 9.1 | - | - | |
Lymph node metastasis | Negative | 7/26 | 110.8 | 1.0 | reference |
Positive | 16/28 | 50.7 | 4.0 | 1.6–11 | |
Lymphatic invasion | Negative | 3/18 | 53.8 | 1.0 | reference |
Positive | 21/40 | 126.1 | 2.4 | 0.7–8.7 | |
Venous invasion | Negative | 8/29 | 127.5 | 1.0 | reference |
Positive | 16/29 | 52.4 | 3.7 | 1.4–10 | |
MUC1 | Negative | 8/27 | 100.6 | 1.0 | reference |
Positive | 16/31 | 79.4 | 1.7 | 0.6–4.6 | |
MUC5AC | Negative | 11/38 | 133.1 | 1.0 | reference |
Positive | 13/20 | 46.8 | 2.5 | 1.1–6.0 | |
MUC16 | Negative | 19/53 | 176.5 | 1.0 | reference |
Positive | 5/5 | 3.4 | 10 | 2.8–39 | |
MUC1/MUC5AC | MUC1(−) and MUC5AC(−) | 7/24 | 83.3 | 1.0 | reference |
MUC1(+) and/or MUC5AC(+) | 17/34 | 96.6 | 1.6 | 0.6–4.3 | |
MUC1/MUC16 | MUC1(−) and MUC16(−) | 8/27 | 100.6 | 1.0 | reference |
MUC1(+) and/or MUC16(+) | 16/31 | 79.4 | 1.7 | 0.6–4.6 | |
MUC5AC/MUC16 | MUC5AC(−) and MUC16(−) | 9/36 | 131.3 | 1.0 | reference |
MUC5AC(+) and/or MUC16(+) | 15/22 | 48.6 | 3.6 | 1.5–8.8 |
*Curability was included in all the statistical models.
NA: not available, D/T: Deaths/Total, P-y: Person-year, HR: Hazard ratio, 95% CI: 95% confidence interval.