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. 2014 Apr 15;25(8):1244–1250. doi: 10.1091/mbc.E13-04-0180

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© 2014 Cai et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 6. — NDPK-B^−/− mice have increased urinary excretion of Ca²⁺. NDPK-B^+/+ or NDPK-B^−/− mice were placed on low- or high-Ca²⁺ diet for 2 wk, after which they were placed in metabolic cages and 24-h urine was collected. Shown is the amount of Ca²⁺ in the urine on a low-Ca²⁺ (Ai) or high-Ca²⁺ (Aii) diet normalized to urinary creatinine. As a control, there was no difference in the amount of Na⁺ (B) or K⁺ (C) excreted in the urine when normalized to urine creatinine on the same samples from mice on a high-Ca²⁺diets. n = 10 mice in each group. Statistics was done in Prism (GraphPad, La Jolla, CA), and t test was used for the significance. *p < 0.05 as compared with the WT.