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. 2014 Apr 10;10(4):e1004274. doi: 10.1371/journal.pgen.1004274

Table 2. 28 verified editing sites in the macaque coding regions.

Position Form Host Gene Recoding Type Function of the Host Gene
1:138950859 A→G COPA I→V non-synonymous change nucleoside-triphosphatase regulator, ion binding, protein binding
6:129544096 A→G ARIH2 K→K synonymous change ion binding, nucleic acid binding, protein binding
6:38781096 A→G RICTOR R→G non-synonymous change protein binding
7:89331048 A→G NOVA1 S→G non-synonymous change, protein stability [51] nucleic acid binding, protein binding
X:150275345 A→G GABRA3 I→M non-synonymous change, trafficking [52] ion binding, protein binding, substrate-specific & transmembrane transporter, neurotransmitter binding, signal transducer
10:26945910 A→G BLCAP Y→C non-synonymous change, cancer biomarker [53] -
10:26945919 A→G BLCAP Q→R non-synonymous change, cancer biomarker [53] -
10:26945949 A→G BLCAP K→R non-synonymous change, cancer biomarker [53] -
11:5028364 A→G KCNA1 affinity for blocking particle, kinetics of channel inactivation [34] ion binding, protein binding, substrate-specific & transmembrane transporter
12:73754116 A→G UNC80 S→G non-synonymous change -
17:24407704 A→G COG3 I→V non-synonymous change protein binding, substrate-specific transporter
5:72269698 A→G IGFBP7 K→R non-synonymous change, proteolytic cleavage [54], physiological properties [23] protein binding
6:153684514 A→G CYFIP2 K→E non-synonymous change, biomarker for ALS [55] protein binding
X:152404069 A→G FLNA Q→R non-synonymous change, physiological properties [23] protein binding, signal transducer
11:47207718 A→G ASIC1 T→A non-synonymous change -
7:54257914 A→G NEIL1 K→R non-synonymous change, nucleotide removal efficiency [36] ion binding, nucleic acid binding, protein binding, hydrolase
7:54257915 A→G NEIL1 K→K synonymous change, nucleotide removal efficiency [36] ion binding, nucleic acid binding, protein binding, hydrolase
5:149561914 A→G GRIA2 Q→R non-synonymous change, Ca-permeability [56], channel trafficking [57], receptor assembly [58] protein binding, substrate-specific & transmembrane transporter, signal transducer
5:149561918 A→G GRIA2 Q→Q synonymous change protein binding, substrate-specific & transmembrane transporter, signal transducer
1:134852231 A→G SMG5 R→G non-synonymous change protein binding
3:13010093 A→G SON L→L synonymous change nucleic acid binding, protein binding
7:43601461 A→G PDCD7 Q→R non-synonymous change -
2:78236903 A→G FLNB M→V non-synonymous change protein binding
4:33833717 A→G GRM4 Q→R non-synonymous change metabotropic glutamate, GABA-B-like receptor, signal transducer
4: 44072645 A→G TMEM63B Q→R non-synonymous change -
8:9841193 A→G XKR6 R→G non-synonymous change -
5:149585132 A→G GRIA2 R→G non-synonymous change protein binding, substrate-specific & transmembrane transporter, signal transducer
X:148223918 C→T NOL11 T→I non-synonymous change -