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. 2014 Apr 10;10(4):e1004052. doi: 10.1371/journal.ppat.1004052

Figure 4. BSOr mutations are located at the interface between protomers.

Figure 4

The poliovirus protomer, shown here as a colored ribbon with VP1 in blue, VP2 in yellow and VP3 in red, forms an interface with symmetry related neighbors, one of which is shown as a mesh with the same color scheme. Three remaining symmetry copies are shown in grey to make up the pentameric arrangement around the 5-fold axis. The locations of the mutations are shown as colored spheres and are predominantly found at the interface between protomers. (A) VP3 Q178L mutation alone; (B) All BSOr PV mutations. Colors: VP3 Q178L-purple; VP1 D219N-Orange; VP3 T175A-Green; VP1 I239V-Pink; VP1 254I-Cyan. Molecular graphics and analyses were performed with the UCSF Chimera package and PyMOL Molecular Graphics System, Version 1.5.0.4 Schrodinger, LLC. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics at the University of California, San Francisco (supported by NIGMS 9P41GM103311) [26], [43].