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. 2014 Apr 10;9(4):e93983. doi: 10.1371/journal.pone.0093983

Figure 9. Increased ERI2 exon 16 inclusion in DM2 patients.

Figure 9

A) EAA analysis identified an AS event on exon 16 of ERI2 mRNA transcript ENST00000261377. The AS area is enlarged and exon 16, more frequently included in DM2 patients, is highlighted in solid gray. B) The box plot shows the increased expression of Affymetrix probe set 3651550 recognizing exon 16, in DM2 patients compared to CTR (n = 10, ** p<0.01). Values are normalized for the levels of the whole transcript. The splice index (SI) is indicated. C) Validation qPCR assays were performed using the specific primer pair indicated as black arrowhead in panel A. Results are shown as fold change (DM2 = 19, CTR = 15; ** p<0.01).