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. 2014 Apr 10;9(4):e93983. doi: 10.1371/journal.pone.0093983

Table 1. Most significant categories and functions.

DISEASE AND DISORDERS p-value
Immunological disease 3.11E-04 -2.13E-02
Neurological disease 3.11E-04 -2.30E-02
Skeletal and Muscular Disorders 3.11E-04 -1.77E-02
Cancer 9.22E-04 -2.46E-02
Reproductive System Disease 9.22E-04 -1.77E-02
MOLECULAR AND CELLULAR FUNCTIONS p-value
Cell Death and Survival 1.05E-04 -2.13E-02
Cellular Development 1.81E-04 -1.83E-02
Cell Morphology 2.85E-04 -1.77E-02
Cellular Movement 5.95E-04 -2.46E-02
Cell-To-Cell Signaling and Interaction 1.25E-03 -2.46E-02
PATHWAYS -log(p-value)
Lanosterol Biosynthesis 1.75E00
Netrin Signaling 1.73E00
Epithelial Adherens Junction Signaling 1.62E00
Fatty Acid Biosynthesis Initiation II 1.46E00
Palmitate Biosynthesis I (Animals) 1.46E00
Urea Cycle 1.46E00
Calcium Signaling 1.42E00
TOP CARDIOTOXIC FUNCTIONS p-value
Increased Levels of Albumin 1.77E-02 -1.77E-02
Increased Levels of Alkaline Phosphatase 1.77E-02 -6.12E-01
Cardiac Arrythmia 4.07E-03 -3.25E-01
Tachycardia 4.07E-03 -3.25E-01
Cardiac Dilation 1.77E-02 -1.45E-01
Congenital Heart Anomaly 1.77E-02 -4.35E-01
Cardiac Hypoplasia 3.95E-02 -3.95E-02