Table 2. EBV EBNA-1 gene prevalence and viral loads in CSF and blood samples of 55 RRMS and 51 controls (OIND + NIND) patients.
| EBV | RRMS | OIND | NIND | RRMS versus OIND | RRMS versus NIND | |||
| P value | OR | P value | OR | |||||
| Plasma | Prevalence (%) | 4/55 (7.3%) | 0/11 (0%) | 3/40 (7.5%) | 0.356 | - | 0.967 | 1 |
| Median * V.L (range) (copies/ml) | 126.5 (98–163) | - | 189 (163–288) | |||||
| PBMC | Prevalence (%) | 26/55 (47.3%) | 7/11 (63.6) | 9/40 (22.5%) | 0.322 | 0.5 | 0.013 | 3.1 |
| Median V.L (range) (copies/106 cells) | 1328 (386–17131) | 1005 (115–4045) | 1412 (40–88506) | |||||
| CSF cell free | Prevalence (%) | 3/55 (5.5%) | 0/11 (0%) | 4/40 (10%) | 0.428 | - | 0.402 | 0.5 |
| Median V.L (range) (copies/ml) | 216 (36–264) | - | 56.5 (14–86) | |||||
| CSF cell ass | Prevalence (%) | 10/55 (18.2%) | 0/11 (0%) | 4/40 (10%) | 0.125 | - | 0.267 | 2 |
| Median V.L (range) (copies/102 cells) | 3 (0.2–25) | - | 3 (1–9) | |||||
PBMC = peripheral blood mononuclear cells; CSF = cerebrospinal fluid; V.L. = viral load; RRMS relapsing-remitting multiple sclerosis; OIND = other inflammatory neurological diseases; NIND = non-inflammatory neurological diseases or normal findings; OR = odd ratio.
*Median refers to positive samples.