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. 2014 Apr 10;9(4):e94548. doi: 10.1371/journal.pone.0094548

Table 1. Comparison of concentration of interferon (IFN)-γ and interleukin (IL)-4 in lymphocytes immunized by NIT-1, NIT-vector and NIT–hAAT cells (pg/mL,Mean±SD. n = 3).

IFN-γ(Th1) IL-4(Th2)
Group NIT-1 NIT-vector NIT-hAAT NIT-1 NIT-vector NIT-hAAT
lymphocytes lymphocytes lymphocytes lymphocytes lymphocytes lymphocytes
NIT-1 218.3±4.9 222.5±3.2 196.1±1.8* 22.8±3.7 23.2±2.7 24.2±4.8*
NIT-vector 223.6±5.1 219.3±4.1 202.1±2.2* 24.6±4.2 27.8±3.4 26.8±4.1*
NIT-hAAT 41.8±3.5** 42.3±4.1** 33.5±5.8** 45.4±2.6** 46.5±2.7** 52.1±3.25**
Control 182.1±6.4 188.1±7.2 164.6±5.2 28.2±0.8 30.7±6.1 32.2±7.2

*P<0·05, NIT-1, NIT-vector group versus Control group;

**P<0·01 NIT-hAAT versus Control, NIT-1 and NIT-vector group. No significant difference between the NIT-1 and NIT-vector groups was observed(P>0.05). No significant difference between the NIT-1primed lymphocytes or NIT-vector primed lymphocytes and the NIT–hAAT primed lymphocytes was observed(P>0.05).