Table 1. Comparison of concentration of interferon (IFN)-γ and interleukin (IL)-4 in lymphocytes immunized by NIT-1, NIT-vector and NIT–hAAT cells (pg/mL,Mean±SD. n = 3).
IFN-γ(Th1) | IL-4(Th2) | |||||
Group | NIT-1 | NIT-vector | NIT-hAAT | NIT-1 | NIT-vector | NIT-hAAT |
lymphocytes | lymphocytes | lymphocytes | lymphocytes | lymphocytes | lymphocytes | |
NIT-1 | 218.3±4.9 | 222.5±3.2 | 196.1±1.8* | 22.8±3.7 | 23.2±2.7 | 24.2±4.8* |
NIT-vector | 223.6±5.1 | 219.3±4.1 | 202.1±2.2* | 24.6±4.2 | 27.8±3.4 | 26.8±4.1* |
NIT-hAAT | 41.8±3.5** | 42.3±4.1** | 33.5±5.8** | 45.4±2.6** | 46.5±2.7** | 52.1±3.25** |
Control | 182.1±6.4 | 188.1±7.2 | 164.6±5.2 | 28.2±0.8 | 30.7±6.1 | 32.2±7.2 |
*P<0·05, NIT-1, NIT-vector group versus Control group;
**P<0·01 NIT-hAAT versus Control, NIT-1 and NIT-vector group. No significant difference between the NIT-1 and NIT-vector groups was observed(P>0.05). No significant difference between the NIT-1primed lymphocytes or NIT-vector primed lymphocytes and the NIT–hAAT primed lymphocytes was observed(P>0.05).