Table 2. The AT1aR regulated pathway maps.
Group | Name of the map | pValue | ratio |
Development | Gastrin in cell growth and proliferation | 5,09E-18 | 22/62 |
Cytoskeleton remodeling | Cytoskeleton remodeling | 5,91E-15 | 24/102 |
Development | FGFR signaling pathway | 1,46E-14 | 18/53 |
Cytoskeleton remodeling | TGF, WNT and cytoskeletal remodeling | 4,51E-14 | 24/111 |
Development | Flt3 signaling | 1,29E-13 | 16/44 |
Development | Thrombopoietin-regulated cell processes | 1,94E-13 | 16/45 |
Regulation of lipid metabolism | Insulin signaling:generic cascades | 4,26E-13 | 16/47 |
Chemotaxis | CXCR4 signaling pathway | 5,98E-13 | 14/34 |
Development | A2B receptor: action via Gprotein alpha s | 1,28E-12 | 16/50 |
Immune response | IL15 signaling | 7,41E-12 | 17/64 |
The phosphopeptides regulated by Ang II or/and SII Ang II was used for enrichment analysis in MetaCore (GeneGo). The enrichment analysis retrieved a list of pathways from the database. The 10 most significant pathways are shown. The majority of the pathways are in good agreement with the current knowledge of angiotensin II signalling.