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. 2014 Apr 10;9(4):e94672. doi: 10.1371/journal.pone.0094672

Table 2. The AT1aR regulated pathway maps.

Group Name of the map pValue ratio
Development Gastrin in cell growth and proliferation 5,09E-18 22/62
Cytoskeleton remodeling Cytoskeleton remodeling 5,91E-15 24/102
Development FGFR signaling pathway 1,46E-14 18/53
Cytoskeleton remodeling TGF, WNT and cytoskeletal remodeling 4,51E-14 24/111
Development Flt3 signaling 1,29E-13 16/44
Development Thrombopoietin-regulated cell processes 1,94E-13 16/45
Regulation of lipid metabolism Insulin signaling:generic cascades 4,26E-13 16/47
Chemotaxis CXCR4 signaling pathway 5,98E-13 14/34
Development A2B receptor: action via Gprotein alpha s 1,28E-12 16/50
Immune response IL15 signaling 7,41E-12 17/64

The phosphopeptides regulated by Ang II or/and SII Ang II was used for enrichment analysis in MetaCore (GeneGo). The enrichment analysis retrieved a list of pathways from the database. The 10 most significant pathways are shown. The majority of the pathways are in good agreement with the current knowledge of angiotensin II signalling.