Table 3. Lipid Levels of Heterozygous Family Members after 6-month 20 mg Simvastatin Treatment.
| Case No | Age (years) | Sex | TC (mmol/L) | TG (mmol/L) | HDL-C (mmol/L) | LDL-C (mmol/L) | LDL-R mutation |
| I-2 | 57 | M | 5.20 | 0.93 | 1.09 | 3.10 | p.Cys356Gly (c.1129T>G) |
| I-3 | 66 | F | 4.75 | 1.21 | 1.13 | 3.87 | p.IIe402Thr (c.1268T>C) |
| II-1 | 28 | F | 4.47 | 1.47 | 1.26 | 4.02 | p.Cys356Gly (c.1129T>G) |
| II-2 | 34 | M | 5.10 | 0.96 | 1.53 | 3.41 | p.IIe402Thr (c.1268T>C) |
| II-3 | 44 | M | 5.01 | 1.38 | 2.01 | 4.11 | p.IIe402Thr (c.1268T>C) |
| III-3 | 23 | M | 3.87 | 1.19 | 1.67 | 3.17 | p.IIe402Thr (c.1268T>C) |
| Normal range | ≤5.20 | ≤1.70 | ≥1.04 | ≤4.12 |
Abbreviations: TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; LDL-R, LDL receptor; TG, triglyceride; M, male; F, female.