TABLE 1.
Variable | Case patients (n = 134) | Control patients (n = 258) | OR (95% CI) | P |
---|---|---|---|---|
Hospital length of stay prior to infection, median (IQR), days | 0 (0–4) | 0 (0–1) | 1.00 (0.99–1.01) | .02 |
Stay at Penn Presbyterian Medical Centera | 48 (35.8) | 70 (27.1) | 1.50 (0.93–2.40) | .08 |
Nonwhite race | 56 (43.4) | 129 (51.2) | 0.71 (0.45–1.12) | .13 |
Hospital onset of infectionb | 40 (29.8) | 60 (23.3) | 1.40 (0.85–2.30) | .18 |
Location in ICU >48 hours prior to infection | 23 (17.2) | 27 (10.5) | 1.77 (0.92–3.37) | .08 |
Inpatient antimicrobial use in prior 30 days | ||||
Vancomycin | 19 (14.2) | 19 (7.4) | 2.08 (1.00–4.32) | .046 |
Piperacillin/tazobactam | 3 (2.2) | 1 (0.4) | 5.89 (0.47–310.10) | .12 |
Extended-spectrum cephalosporinc | 12 (9.0) | 12 (4.6) | 2.02 (0.80–5.06) | .12 |
Aztreonam | 3 (2.2) | 1 (0.4) | 5.89 (0.46–310.10) | .12 |
Levofloxacin | 21 (15.7) | 15 (5.8) | 3.01 (1.42–6.51) | .003 |
Aminoglycosided | 10 (7.5) | 7 (2.7) | 2.89 (0.96–9.15) | .04 |
Metronidazole | 14 (10.4) | 16 (6.2) | 1.76 (0.77–4.00) | .16 |
NOTE. Data are no. (%) of patients, unless otherwise indicated. Only variables with P less than .20 are shown. The Fisher exact test was used for categorical variables and the Wilcoxon rank-sum test for continuous variables. CI, confidence interval; ICU, intensive care unit; IQR, interquartile range; OR, odds ratio.
As opposed to the Hospital of the University of Pennsylvania.
Onset of infection more than 48 hours after hospital admission.
Ceftriaxone, cefotaxime, or cefepime.
Amikacin, gentamicin, tobramycin.