Figure 9. ROS levels in pancreatic acini isolated from WT and UCP2^-/- mice.

DCFH-DA-labeled pancreatic acini of 12 months old WT and UCP2^-/- mice were treated in vitro with cerulein at the indicated concentrations for 30 min before fluorescence intensity of 2′,7′-dichlorofluorescein was recorded. Data of 6 independent samples per experimental protocol were used to calculate mean values ± SEM. *P<0.05 (WT versus corresponding UCP2^-/- mice).