Figure 2.

Schematic representation of metabolic steps involved in lipid accumulation in yeasts. The diagram also includes the connection between fatty acid synthesis, triacylglycerol synthesis, and lipid droplet formation. Abbreviations: ME, malic enzyme (cytosolic); ME 2, malic enzyme (ER membrane, responsible for fatty acid desaturation); ACL, ATP:citrate lyase; ID, isocitrate dehydrogenase; NLD, nascent lipid droplet; LD, lipid droplet; ER, endoplasmic reticulum; LPA, lysophosphatidic acid; PA, phosphatidic acid, FAS I, fatty acid synthase I; DAG, diacylglycerol; TAG, triacylglycerol; AMPD, AMP deaminase.