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. 2014 Feb 25;57(6):2393–2412. doi: 10.1021/jm401712t

Table 7. Stability of Selected Compounds to Metabolism by Mouse Liver Microsomesa.

compd % rem (15 min)a T1/2 (min)b
15g 0.2 1.6
3k 1.2 2.8
3e 20 7.0
5c 30 8.0
a

Percent of the parent compound remaining after 15 min incubation. The initial concentration of the parent compound was 1 μM.

b

Half-life (minutes) of parent compound.