Table 3. Inhibition Profile of 2155-14 and 2155-18 with Melanoma Cell Lines Carrying Different Mutationsa.
| compound | M14 | SKMEL-28 | B16/F10 |
|---|---|---|---|
| 2155-14 | 3.6 ± 0.3 | 0.56 ± 0.04 | 2.7 ± 0.2 |
| 2155-18 | 0.89 ± 0.07 | 0.75 ± 0.06 | 1.15 ± 0.08 |
Data are reported as the mean of three experiments ± standard deviation. Units are IC50 in micromolar.