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. 2014 Jan 28;57(4):1599–1608. doi: 10.1021/jm4019542

Table 3. Inhibition Profile of 2155-14 and 2155-18 with Melanoma Cell Lines Carrying Different Mutationsa.

compound M14 SKMEL-28 B16/F10
2155-14 3.6 ± 0.3 0.56 ± 0.04 2.7 ± 0.2
2155-18 0.89 ± 0.07 0.75 ± 0.06 1.15 ± 0.08
a

Data are reported as the mean of three experiments ± standard deviation. Units are IC50 in micromolar.