Table 3:

Cyst size distribution was shifted towards higher proportions of small cysts after 3 months of tolcapone treatment

	Relative group size in (%)								Differences between the relative group sizes
Substrain	PKD/Mhm				PKD/US				PKD/Mhm		PKD/US
Sex	Male		Female		Male		Female		Male	Female	Male	Female
Cyst size in (mm2)	T	C	T	C	T	C	T	C	Difference (treated-control)
<0.010	18.3	16.6	6.9	29.4	11.6	5.9	6.0	9.1	1.6	−22.5	5.8	−3.1
0.010–0.019	22.5	16.8	17.8	15.1	17.4	10.2	11.6	17.2	5.7	2.7	7.1	−5.6
0.020–0.029	16.9	16.2	18.4	14.2	19.5	17.1	22.4	21.6	0.7	4.2	2.3	0.8
0.030–0.049	16.4	17.8	22.3	16.3	19.8	22.5	25.7	22.0	−1.4	6.1	−2.7	3.6
0.050–0.100	12.9	17.5	20.8	14.9	17.1	23.2	23.5	19.8	−4.6	5.9	−6.2	3.7
>0.100	13.0	15.1	13.7	10.1	14.7	21.1	10.8	10.2	−2.1	3.7	−6.4	0.6
total	100	100	100	100	100	100	100	100

Cyst sizes were divided to obtain six groups with approximately equal group sizes in the control animals.