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Human epidermal growth receptor family members, the PI3K/Akt pathway, and targeted drugs. HER: Human epidermal growth receptor; NK: Natural killer; IGF1R: α-insulin-like growth factor 1-receptor; EGFR: Epidermal growth factor receptor; PI3K: Phosphatidylinositol-3-kinase; PTEN: Phosphatase and tensin homologue.
