Table 10.
Results of Cox proportional hazards model for multivariate regression analysis
| Prognostic factor | Parameter estimate | Wald χ2 | P value | HR | 95%CI |
| CEA | -0.043 | 0.498 | 0.48 | 0.957 | 0.849-1.080 |
| CA199 | 0.005 | 12.076 | 0.001 | 1.005 | 1.002-1.009 |
| CA242 | -0.007 | 0.386 | 0.535 | 0.993 | 0.972-1.015 |
| CA125 | 0.003 | 0.714 | 0.398 | 1.003 | 0.996-1.009 |
| Surgical modality | 0.569 | 2.450 | 0.118 | 1.766 | 0.866-3.599 |
| LN metastasis | 1.191 | 3.276 | 0.07 | 3.291 | 0.906-11.957 |
| Position (neck) | -1.578 | 6.358 | 0.012 | 0.206 | 0.061-0.704 |
| Age | -0.010 | 0.073 | 0.787 | 0.990 | 0.922-1.063 |
| Sex | 0.796 | 2.508 | 0.113 | 2.216 | 0.828-5.932 |
Multivariate survival analysis using the Cox proportional hazards model for independent prognostic factors of gallbladder cancer (GBC). P < 0.05 was considered statistically significant. CA: Cancer antigen; CEA: Carcinoembryonic antigen; LN: Lymph node.