Table 1.
Reversible variations in marrow cell phenotype with cell cycle phase after engraftment into lethally irradiated mice.
| Characteristic | Whole marrow | LRH | Lin-Sca-1+ |
|---|---|---|---|
| Engraftment | Nadir late S/early G2 | Nadir late S/early G2 first and second cycles with recovery in between | |
| Homing | Nadir late S/G2 second cycle | ||
| Increase in lung conversion | Early S-phase | ||
| Differentiation into megakaryocyte and proliferative granulocytes | Around G1/S interface | ||
| Differentiation into non-proliferative granulocytes | Late S-phase |