Table 2. Mean numbers of particular cell types in tears during the positive SIKCR and PBS control challenge (n=23).
| Before the challenge |
After the challenge (min) |
|||||||
|---|---|---|---|---|---|---|---|---|
| 0–10 | 20–30 | 60 | 90 | 120 | 180 | 240 | ||
| Eosinophils | ||||||||
| SIKCR | 1 | 2 | 3.0* | 4.0* | 3.0* | 0 | 0 | 0.5 |
| PBS | 0.5 | 0 | 0.5 | 0 | 0 | 0.5 | 0 | 0.5 |
| Neutrophils | ||||||||
| SIKCR | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 |
| PBS | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Mast cells | ||||||||
| SIKCR | 0 | 1.5* | 1.5* | 0 | 0 | 0 | 0 | 0 |
| PBS | 0 | 0 | 0.5 | 0 | 0 | 0 | 0 | 0 |
| Conjunctival EC | ||||||||
| SIKCR | 0 | 0 | 0 | 1 | 2* | 3* | 0 | 0 |
| PBS | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Abbreviations: EC, epithelial cells; PBS, phosphate-buffered saline; SIKCR, secondary immediate keratoconjunctival response.
Significance with respect to the baseline (before the challenge): *P<0.05.