Table 1.
Study set overview
| Genotype | Samples |
|---|---|
|
mitf:BRAF
V600E
|
1 |
|
mitf:BRAF
V600E
;p53
+/-
|
2 |
|
mitf:BRAF
V600E
;p53
+/-
; ptena
hu1874
+/-
|
1 |
|
mitf:BRAFV600E;mitf vc7+/+; |
4 |
|
mitf:BRAFV600E;mitf vc7+/+;p53+/- |
4 |
|
mitf:BRAFV600E; p53-/-;mitf -/-;mitf:MITF |
6 |
|
mitf:BRAFV600E;p53-/-;mitf -/-;mitf:MITF;mitf:foxd3 |
4 |
|
mitf:BRAFV600E;p53-/-;mitf -/-;mitf:MITF;mitf:krox20 |
12 |
|
mitf:BRAFV600E;p53-/-;mitf -/-mitf:MITF;mitf:krox20/foxd3/OCT6* |
1 |
|
mitf:BRAFV600E;p53-/-;mitf -/-;mitf:MITF;mitf:SETDB1 |
1 |
|
mitf:BRAFV600E;p53-/-;mitf -/-;mitf:MITF;mitf:EGFP |
1 |
|
mitf:NRAS1
Q61K
|
2 |
|
mitf:NRAS1
Q61K
;p53
-/-
|
5 |
|
mitf:NRAS1
Q61K
;p53
+/-
|
4 |
|
mitf:NRAS1
Q61K
;p53
+/-
;rps29
+/-
|
5 |
| Total | 53 |
The asterisk indicates that the genes krox20, foxd3 and OCT6 were each expressed on separate plasmids for this tumor.