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. 2013 Dec 22;15(1):70–76. doi: 10.1002/embr.201337642

Figure 3. Direct transcriptional regulation oflncRNAs by HIF.

Figure 3

  • A Heat map showing fold regulation by hypoxia and by the indicated HIF siRNA for lncRNAs adjacent to HIF-binding site that are detected in the polyA RNA-seq analyses.
  • B, C RNA-seq and HIF ChIP-seq genome browser tracks for the two most hypoxically upregulated HIF-binding lncRNAs: (B) MALAT1 and (C) NEAT1.