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. Author manuscript; available in PMC: 2015 Jan 8.
Published in final edited form as: J Am Chem Soc. 2013 Dec 16;136(1):188–194. doi: 10.1021/ja407858c

Fig. 5.

Fig. 5

Hydration and protein dynamics of HEWL-RC in crowding conditions plotted as a function of protein-protein distance. a, The protein-protein distance is defined as the average surface-to-surface distance between proteins using a spherical approximation, which can be estimated for each concentration. b, Assuming a homogeneous mixture, the average surface-to-surface distance between proteins can be estimated, revealing that the transition occurs at a protein-protein distance of 30-40 Å.