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(A) Dose response for frequencies of micronuclei and binucleated cells at low doses of MMC. A LOGEL was found at 4.8 µg/ml (P = 0.004). Subsequent broken stick modelling (B) of these data did not discount a linear response for micronucleus induction (P = 0.3). *Represents a P ≤ 0.05 relative to the untreated control.
