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. 2014 May;95(Pt 5):1025–1032. doi: 10.1099/vir.0.061952-0

Table 1. Cross-neutralization of sera from rabies vaccinated humans and animals against IKOV.

Neutralizing antibody titres against RABV (Challenge virus standard, CVS) and IKOV in reciprocal 50 % end point titres. International units (IU) are given for rabies by comparison to a standard control (not applicable to IKOV). Mice 3, 4 and 5 were inoculated IM with IKOV at 103.8 TCID50 ml−1 and survived. Rabbit 821 is rabbit anti-WCBV serum with a reciprocal titre of 1448 against WCBV. nd, not done.

Virus
CVS (100 TCID50) IKOV (100 TCID50)
Sample ID IU ml−1 Reciprocal titre Reciprocal titre
HUMAN - 1 23 959 <8
HUMAN - 2 31 1 263 <8
HUMAN - 3 1 093 34 092 <8
HUMAN - 4 1 093 34 092 <8
DOG 1 53 1 263 <8
DOG 2 41 960 <8
DOG 3 1 094 25 904 <8
DOG 4 122 2 878 <8
DOG 5 365 8 635 <8
DOG 6 1 16 <8
DOG 7 1 094 34 109 <8
DOG 8 364 11 364 <8
DOG 9 14 421 <8
DOG 10 41 1 263 <8
HRIG 270 nd <16
Mouse 3 <0.2 <16 27
Mouse 4 <0.2 <16 420
Mouse 5 nd nd 81
Rabbit 821 <0.2 <16 <8