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. 2014 May;95(Pt 5):1083–1093. doi: 10.1099/vir.0.063560-0

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© 2014 The Authors

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 6. — Maternal immunization with inactivated CA16CC024 virus protected newborn mice from lethal challenge with (a) CC045, (b) CC090, (c) CC097 and (d) CC163 (d). Adult female ICR mice were immunized twice at 2 week intervals and allowed to mate with male mice after the first injection. After delivery, pups (n = 8–10) were challenged with the lethal strain. Clinical scores and survival rates were monitored for 21 days post-challenge.