Figure 3.

MTL activity separated by task condition. Task-induced activity in hippocampus (red/yellow) and task-induced deactivations (blue) in entorhinal cortex separated by task-condition. Bar graphs show averaged activity for encoding hit, encoding miss, retrieval hit, and retrieval miss in young (YNG) and older adults with low (Aβ−) and high (Aβ+) amounts of amyloid-β deposition. Top shows activations averaged across the left and right hippocampus and demonstrated no significant differences between Aβ− and Aβ+ older adults. Bottom shows deactivations, averaged across the left and right entorhinal cortex. Note that the pattern was similar across all task-conditions and an ANOVA revealed no significant interactions between amyloid-β status and encoding/retrieval or hit/miss. Middle panel is reproduced from Figure 2.