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. 2014 Mar 15;189(6):727–740. doi: 10.1164/rccm.201401-0065ST

Table 1:

Overview of Methods Used for Guideline Development

  Yes No
Panel assembly    
 • Included experts for relevant clinical and nonclinical disciplines X  
 • Included individual who represents the views of patients and society at large   X
 • Included a methodologist with appropriate expertise (documented expertise in conducting systematic reviews to identify the evidence base and the development of evidence-based recommendations) X  
Literature review    
 • Performed in collaboration with librarian   X
 • Searched multiple electronic databases X  
 • Reviewed reference lists of retrieved articles X  
Evidence synthesis    
 • Applied prespecified inclusion and exclusion criteria X  
 • Evaluated included studies for sources of bias X  
 • Explicitly summarized benefits and harms X  
 • Used PRISMA1 to report systematic review   X
 • Used GRADE to describe quality of evidence X  
Generation of recommendations    
 • Used GRADE to rate the strength of recommendations X  

Definition of abbreviations: GRADE = Grading of Recommendations Assessment, Development, and Evaluation; PRISMA1 = Preferred Reporting Items for Systematic Reviews and Meta-Analyses, version 1.