TABLE 2.
Comparison of patients undergoing CRS/HIPEC with and without ureteral stents
| Characteristic | No stents (n = 310) | Stents (n = 550) | p Value |
|---|---|---|---|
| Age (years), mean ± SD | 52.4 ± 13.1 | 53.4 ± 12.0 | 0.23 |
| Gender, n (%) | 0.62 | ||
| Male | 148 (47.7) | 252 (45.8) | |
| Female | 162 (52.3) | 298 (54.2) | |
| Body mass index (kg/m2), mean ± SD (n = 706) | 28.2 ± 6.0 | 27.7 ± 6.6 | 0.22 |
| ECOG performance status, n (%) (n = 831) | 0.13 | ||
| 0 | 148 (49.5) | 224 (42.1) | |
| 1 | 117 (39.1) | 227 (42.7) | |
| 2–4 | 43 (14.4) | 93 (17.5) | |
| Malnutrition, n (%)a | 44 (14.2) | 165 (30) | <0.001 |
| Preoperative chemotherapy, n (%) (n = 767) | 76 (28.8) | 181 (36.0) | 0.05 |
| Prior surgical score, n (%) (n = 831) | 0.1 | ||
| 0 | 127 (42.5) | 186 (35.0) | |
| 1 | 52 (17.4) | 100 (18.8) | |
| 2–3 | 120 (40.1) | 246 (46.2) | |
| Site of primary disease, n (%) | <0.001 | ||
| Appendix | 127 (41.0) | 276 (50.2) | |
| Colon | 62 (20.0) | 137 (24.9) | |
| Ovary | 29 (9.4) | 29 (5.3) | |
| Mesothelioma | 15 (4.8) | 41 (7.5) | |
| Other/unknown | 77 (24.8) | 67 (12.2) | |
| More than 1 CRS/HIPEC, n (%) | 26 (8.4) | 38 (6.9) | 0.42 |
| Resection status, n (%) (n = 835) | <0.001 | ||
| R0/1 | 181 (59.9) | 200 (37.5) | |
| R2 | 121 (40.1) | 333 (62.5) | |
| Length of procedure (h), mean ± SD (n = 599) | 7.1 ± 2.6 | 9.1 ± 3.2 | <0.001 |
| Total no. of organs resected, mean ± SD | 2.7 ± 1.6 | 3.3 ± 1.8 | <0.001 |
| Rectal resection, n (%) | 12 (3.9) | 58 (10.5) | <0.001 |
| Resection of uterus, n (%) | 24 (7.7) | 52 (9.5) | 0.45 |
| Estimated blood loss (mL), mean ± SD (n = 633) | 554 ± 614 | 875 ± 754 | <0.001 |
| No. of days in ICU, mean ± SD (n = 646) | 2.3 ± 7.1 | 4.1 ± 10.3 | <0.001 |
| No. of days in hospital, mean ± SD (n = 852) | 12.1 ± 12.9 | 16.0 ± 19.1 | <0.001 |
CRS/HIPEC cytoreductive surgery–hyperthermic intraperitoneal chemotherapy, SD standard deviation, ECOG Eastern Cooperative Oncology Group, ICU intensive care unit
a
Malnutrition was defined as prealbumin <18 mg/dL, albumin <3 g/dL, or presence of cachexia