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Structure of the major mammalian retrotransposons. Mouse and human examples of the three different classes of mammalian retrotransposon (LINE, SINE, LTR) are shown. Transcription regulatory regions are indicated with filled rectangles, and the main protein coding regions with open rectangles. Transcriptional start sites are shown with an arrow. Some LTR retrotransposons, e.g. IAP, have lost the env gene present in their infectious progenitors [241]. LTR long terminal repeat
