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High activity rats show increased hypothalamic galanin, enkephalin and orexin mRNA, as assessed by qRT-PCR (Experiment 2A). Values are mean ± S.E.M. **p < 0.01 vs. low subgroup; *p < 0.05 vs. low; +p < 0.05 vs. middle. Abbreviations: ARC, arcuate nucleus; ENK, enkephalin; GAL, galanin; MCH, melanin-concentrating hormone; NPY, neuropeptide Y; OX, orexin; PFLH, perifornical lateral hypothalamus; PVN, paraventricular nucleus of the hypothalamus.
