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. Author manuscript; available in PMC: 2014 Nov 14.
Published in final edited form as: J Med Chem. 2013 Oct 23;56(21):8257–8269. doi: 10.1021/jm400898x

Table 3. Activity of acyclic phenethyl-1,2,3-TUs.

graphic file with name nihms534552u3.jpg
Structure Compound DAGLB % Inhibition (100 nM) Off-targets (10 μM)
graphic file with name nihms534552t1.jpg 35 69.9 ABHD6, 80 kDa SH, PLA2G7
graphic file with name nihms534552t2.jpg 36 70.5 FAAH, KIAA1363, ABHD6, 80 kDa SH, PLA2G7
graphic file with name nihms534552t3.jpg 37 73 ABHD6, 80 kDa SH, PLA2G7
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