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| Aging-related comorbidities | Chronic HIV infection | Rheumatoid arthritis |
|---|---|---|
| Cancer | ++ | ? |
| Cardiovascular disease | ++ | ++ |
| Metabolic syndrome | ++ | ++ |
| Infectious risk | ++ | ++ |
| Reduced vaccine response | ++ | ++ |
| Bone loss | ++ | ++ |
| Neurocognitive decline | ++ | ? |
| Frailty | ++ | ++ |
| Shortened life expectancy | ++ | ++ |
