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. Author manuscript; available in PMC: 2015 Mar 15.
Published in final edited form as: Bioorg Med Chem. 2014 Jan 9;22(6):1960–1972. doi: 10.1016/j.bmc.2014.01.001

Figure 3.

Figure 3

Dose-response curves for potency (EC50 by ELISA; filled circles) and cell viability (LC50 by calcein assay; open circles) for two potent confirmed SPC hits in T98G cells from each of three representative scaffolds: amide (A and B), aminothiazole (C and D), and chromene (E and F). Percentages were normalized to the maximal absorbance measured at the highest concentration tested. See Table 3 for exact EC50 values.