Table 8. Association of DRB1 SNP-Strings with MS (US particcipants)*.
DRB1 | |||||||
SNP-Strings | |||||||
a1 | a2 | a3 | a4 | a7 | a8 | a9 | |
Cases | |||||||
0-copies | 405 | 250 | 332 | 357 | 361 | 417 | 453 |
1-copy | 64 | 188 | 125 | 106 | 105 | 53 | 19 |
2-copies | 3 | 34 | 15 | 9 | 6 | 2 | 0 |
Controls | |||||||
0-copies | 319 | 329 | 272 | 323 | 278 | 353 | 393 |
1-copy | 93 | 81 | 125 | 87 | 123 | 60 | 22 |
2-copies | 3 | 5 | 18 | 5 | 14 | 2 | 0 |
OR 1 allele | 0.54 | 3.05 | 0.82 | 1.10 | 0.66 | 0.75 | 0.75 |
OR 2 alleles | 0.79 | 8.95 | 0.68 | 1.63 | 0.33 | 0.85 | na** |
X2 (1 df) 1 allele | 11.9 | 52.5 | 1.8 | 0.4 | 7.4 | 2.1 | 0.8 |
X2 (1 df) 2 allele | 0.1 | 28.2 | 1.1 | 0.8 | 5.5 | 0 | na** |
*Data is taken from the “complete” analysis (see text). Only selected SNP-strings are displayed.
**na = not available (has a zero divisor).