Figure 3.

(A) Scatter plot analysis of the relationship between NTCRs in donor hepatocytes and those in recipient hepatocytes. A regression line was obtained from all of the paired subjects (n = 12), y (recipient NTCR) = 0.62x(donor NTCR)+0.26, (r = 0.765, R² = 0.544, p = 0.0038), shown by a solid black line. By using model 1: Y = β₀+β₁X₁ (age)+β₂ X₂ (group), that related Y (recipient NTCR) to X₁ (donor NTCR) and X₂ (group), given that the value for the comparable group was 1 and that for the lower group was 0. This model yielded a regression line from the comparable patient group (n = 8): Y (recipient NTCR) = −0.10+0.79X(donor NTCR) +0.32, shown by a red line; and a regression line from the lower patient group (n = 4): Y (recipient NTCR) = −0.10+0.79X (donor NTCR), shown by a blue line. The difference of recipient NTCR values between the groups was 0.32 and significant (P = 0.001). Red circles: the recipient-donor pair categorized as the comparable NTCR group. Blue circles: the recipient-donor pair categorized as the lower NTCR group. (B) Comparison between donors in the comparable group and those in the lower group by age factor. The difference of donor ages (median values) between the groups was 5 y 6 m and significant (p = 0.017). Red circles, the donors categorized as the comparable NTCR group. Blue circles, the donors categorized as the lower NTCR group.