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. 2014 Apr 11;9(4):e93749. doi: 10.1371/journal.pone.0093749

Table 2. Clinical and pathological status of donors and recipients.

Group Pair No. Major complication of recipient Pathological findings Immunosuppression status
Lower NTCR Group Donor (-)
1 Recipient Chronic hepatitis Mild interface hepatitis Tacrolimus: twice a day
de novo HBV Micophenolate mofetil
Donor (-)
2 Recipient Mild interface hepatitis Tacrolimus: twice a day
Micophenolate mofetil
Steroid
Donor (-)
3 Recipient Tacrolimus: twice a day
HV stenosis Marked bridging fibrosis Micophenolate mofetil
Steroid
Donor (-)
4 Recipient Unstable liver function Mild lobular hepatitis Cyclosporine: twice a day
Micophenolate mofetil
Comparable NTCR Group Donor Moderate steatosis
5 Recipient de novo HBV (-) Cyclosporine: twice a day
(seroconversion) Micophenolate mofetil
Donor
6 Recipient Liver dysfunction Marked bridging fibrosis Tacrolimus: twice a day
HV stenosis Micophenolate mofetil
Steroid
7 Donor (-)
Recipient None Mild interface hepatitis Tacrolimus: twice a day
Donor Moderate steatosis
8 (NASH suspected)
Recipient Biliary stricture Canalicular cholestasis Cyclosporine: twice a day
Donor (-)
9 Recipient HV stenosis Mild interface hepatitis Cyclosporine: twice a day
Micophenolate mofetil
10 Donor (-)
Recipient None (-) Complete cessation
11 Donor (-)
Recipient None (-) Tacrolimus: once a week
Donor Moderate steatosis
12 Recipient Unstable liver function (-) Tacrolimus: twice a day
Micophenolate mofetil

HBV: hepatitis B virus, HV: hepatic vein, NTCR: normalized telomere centromere ratio, NASH: none-alcoholic steatotic hepatitis, (-): almost normal.

Lower NTCR group: Median NTCRs of the recipient hepatocyte was significantly lower than those of the donor.

Compatible NTCR group: Median NTCRs of the recipient hepatocyte was not significantly lower nor higher than those of the donor.