Table 2. Association between measures of BP and ICA blood velocity parameters.

Values are standardized β (p value, FDR correctedpvalues) for the sitting BP measures predicting ICA blood velocity measures after accounting for covariates. See Supplementary Table S3 for full covariate effects.

	Blood velocity in the ICA
BP Measures	Systolic velocity	Mean velocity	Diastolic velocity	Pulsatility index	Resistivity index
Wave 1
Systolic BP	0.06 (0.141,0.256)	0.04 (0.285,0.407)	0.01 (0.76,0.80)	0.04 (0.335,0.447)	0.04 (0.256,0.394)
Mean BP	−0.04 (0.245,0.394)	−0.02 (0.647,0.711)	0.02 (0.533,0.627)	−0.11 (0.003,0.009) *	−0.08 (0.054,0.111)
Diastolic BP	−0.13 (0.001,0.003) *	−0.07 (0.068,0.120)	0.03 (0.423,0.529)	−0.24 (<0.0001,<0.0005) *	−0.18 (<0.0001,<0.0005) *
Pulse pressure	0.15 (<0.0001,<0.0005) *	0.09 (0.011,0.028) *	−0.01 (0.887,0.88)	0.19 (<0.0001,<0.0005) *	0.17 (<0.0001,<0.0005) *
Wave 2
Systolic BP	0.02 (0.536,0.596)	−0.01 (0.757,0.850)	−0.06 (0.114,0.147)	0.11 (0.004,0.014) *	0.10 (0.013,0.022) *
Mean BP	−0.10 (0.009,0.018) *	−0.10(0.008,0.018) *	−0.08 (0.029,0.031) *	−0.04 (0.349,0.400)	−0.01 (0.722,0.75)
Diastolic BP	−0.20 (<0.0001,<0.0005) *	−0.17 (<0.0001,<0.0005) *	−0.09 (0.024,0.029) *	−0.18 (<0.0001,<0.005) *	−0.12 (0.002,0.003) *
Pulse pressure	0.13 (<0.0001,<0.004) *	0.11 (0.004,0.010) *	0.05 (0.217,0.271)	0.12 (0.002,0.007) *	0.10 (0.012,0.022) *

^*represent associations that remained significant after applying a correction for false discovery rate.