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. 2014 Apr 11;9(4):e93847. doi: 10.1371/journal.pone.0093847

Table 5. Summary of post-test probability according to the prevalence and predicted positive likelihood ratio.

Prevalence of culture-positive PTB Prediction Score Pre-test odds LR+ Post-test odds Post-test probability
Study population in derivation phase 3.2%a 1 0.033 328.33 10.82 91.5%
Study population in validation phase 3.6%b 1 0.037 328.33 12.26 92.5%
High prevalence 5.0% 1 0.053 328.33 17.28 94.5%
Moderate prevalence 3.0% 1 0.031 328.33 10.15 91.0%
Moderate-to-low prevalence 1.0% 1 0.010 328.33 3.32 76.8%

LR+, predicted positive likelihood ratio. The LR+ = 328.33 derived from the equation (sensitivity/1-specificity) with a sensitivity = 98.5% and specificity = 99.7% in derivation phase.

a

The prevalence was calculated based on the culture-positive PTB probability in the derivation phase (132/4140).

b

The prevalence was calculated based on the culture-positive PTB probability in validation phase (147/4105).