Skip to main content
. Author manuscript; available in PMC: 2014 Apr 11.
Published in final edited form as: Immunol Res. 2013 Mar;55(0):22–33. doi: 10.1007/s12026-012-8346-y

Table 1.

CD8 tumor-infiltrating lymphocytes correlate with patient survival

Cancer type CD8 TIL counts Patient survival (months) Correlation No. of patients References
Colorectal 100–400 cells per mm2 10–35 Lower cell density correlates with tumor recurrence 415 [113]
Metastatic melanoma 35 % of total T cells in tumor 23–130 Decrease in survival when CD8 TILs are around tumor versus throughout tumor 147 [114]
Glioblastoma 1–10 cells per mm2 30–40 Increase in CD8 TILs correlates with increase in malignancy 93 [115]
Lung 0.4–45 cells per mm2
Median = 10.8 cells		 240 (20–40 % survival) Higher survival in patients with CD8 TILs >median 99 [116]
Ovarian 0–89.5 cells per field
Median = 7.60 cells		 25.5–54.9 Higher survival correlates with higher intraepithelial CD8 TILs 117 [117]
Breast 90–557 cells per field 240 (50–70 % survival) Higher survival in patients with CD8 TILs and correlation with grade 1334 [118]