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. 2014 Apr 11;9(4):e94513. doi: 10.1371/journal.pone.0094513

Table 1. Thermodynamic parameters of two Ca2+ binding sites in M-crystallin monomer and octamer.

Parameter Monomer Octamer
Kd1 (µM) 31±7 31±6
ΔH1 (kcal/mol) −7.7±0.1 −8.5±0.1
ΔS1 (cal/mol/K) −5.2±0.8 −7.9±0.8
ΔG1 (kcal/mol) −6.2±0.2 −6.2±0.2
Kd2 (µM) 200±60 166±60
ΔH1 (kcal/mol) −3.2±0.1 −3.2±0.1
ΔS1 (cal/mol/K) 6.2±1.0 6.6±1.1
ΔG2 (kcal/mol) −5.0±0.2 −5.2±0.2