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Progesterone (A), DHEA (B), androstenedione (C), estradiol (D), estriol (E), and estrone (F) production by H295R and BeWo cells in monoculture or in co-culture over a 24-hr period. Hormone concentrations (pg/mL) are presented as mean ± SE (progesterone, n = 4; DHEA, androstenedione, estriol, and estrone, n = 3; estradiol, n = 5). *p < 0.05. **p < 0.01. #p < 0.001.
