Table 3.
Population distribution by minor allele carriers and homozygous major allele carriers for GSTP1 and TNF (pooled data).
SNP genotype | No. of children | Current asthma cases [n (%)] | Children in the highest tertile of NO2 (n) | Children with current asthma in the highest tertile of NO2 [n (%)] |
---|---|---|---|---|
GSTP1 rs1138272 | ||||
TT/TC | 789 | 80 (10.1) | 224 | 15 (6.7) |
CC | 3,807 | 287 (7.5) | 1,144 | 57 (5.0) |
GSTP1 rs1695 | ||||
GG/GA | 2,740 | 199 (7.3) | 873 | 34 (3.9) |
AA | 2,008 | 170 (8.5) | 618 | 39 (6.3) |
TNF rs1800629 | ||||
AA/AG | 1,411 | 119 (8.4) | 421 | 31 (7.4) |
GG | 3,072 | 244 (7.9) | 917 | 40 (4.4) |