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Figure 9. Growth inhibition of mesothelin-antigen expressing tumor cell lines. Mesothelin-antigen stably overexpressing HT29 cells were incubated with mesothelin-IgG based immunoRNase fusion protein. CTX-IgG-RNase was used as negative control. Mesothelin-IgG conjugated to a maytansinoid-based toxophore was used as positive control.
