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. 2014 Jan 3;6(2):392–402. doi: 10.4161/mabs.27705

Table 1. Summary of antibody binding to different HER2 receptor constructs.

graphic file with name mabs-6-392-t1.jpg

Wild-type; hu-HER2, I; hu-HER2-ch(I), II; hu-HER2-ch(II), III; hu-HER2-ch(III), IV; hu-HER2-ch(IV) +++ Indicates wild-type binding or binding similar to wild-type binding, ++ indicates reduced EC50 but similar maximal binding compared with wild-type binding, - indicates no binding detected. See Figure S1 for dose-response binding curves.