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| VH glycosylation in IgG expressed in: | |||
|---|---|---|---|
| Variant | Sequencea | 293 cells | CHO cells |
| MSL-109 | NSDST | No | NDb |
| D53S | NSSST | Yes | Yes |
| D53N | NSNST | Yes | Yes |
| T55R | NSDSR | No | ND |
| D53S/T55R | NSSSR | Partial | Partial |
| D53N/T55R | NSNSR | No | ND |
aSequence between heavy chain Kabat positions 52 and 55 shown. Potential glycosylation sites are underlined. Mutations from MSL-109 are highlighted. b Not determined.
