Table 5. (A) Comparative VH regions of human mAb for human cytomegalovirus. (B) Comparative VL regions of human mAb for human cytomegalovirus.
BD, blood donor; bold mAb number, neutralizing activity; underlined text, CDR regions; blue text, changes from CDR germline; orange text, changes from Framework germline; boxed residues, part of antigen contact determined by X-ray crystal structure analysis; *boxed residues for ITC88 are based on homology to mAb 8F9 binding AD-2S1 peptide (69ETIYNTTLKY78)