Table 3. Antibody thermodynamic values and stoichiometry for target binding.

Antibody	ΔG (kJ/mol)	ΔH (kJ/mol)	-TΔS (kJ/mol)	Stoichiometry (N)
Ch-mAb7F9	-43	-45	1	1.89
Matuzumaba	-47	-77	30	1.78
Cetuximaba	> -50	-70	< 20	1.76
Panitumumaba	> -49	-48	< -1	1.68
mAb08b	-49	-117	68	0.84

^a Data from or calculated from Alvarenga et al.^13bData derived from Ramakrishnan et al.¹⁴