Table 6. METH pharmacokinetic values after SC METH administration and ch-mAb7F9 treatment.
Treatment Group | Vdss (mL/kg) | ClT (mL/kg/hr) | t1/2λz (hr) |
---|---|---|---|
Ch-mAb7F9 15 mg/kg | 1881 | 575 | 2.3 |
Ch-mAb7F9 150 mg/kg | 365 | 38.6 | 6.5 |
MAb7F9 150 mg/kg | 391 | 75.2 | 3.6 |
METH alonea | 9000 | 7560 | 1.1 |
a METH pharmacokinetic values are from Riviere et al.21